View drug interactions between caffeine and tylenol. These medicines may also interact with certain foods or diseases. Sep 28, 2007 · consuming large amounts of caffeine while taking acetaminophen, a widely used painkiller, could potentially cause liver damage, according to a preliminary laboratory study. Sep 27, 2007 · a mix of acetaminophen and caffeine may cause liver damage, especially in heavy caffeine drinkers, according to a preliminary study conducted by the university of washington in seattle.
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